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W221 Sedan
Mercedes-Benz S-Class · Sedan · 2005–2013
Big-tech S-Class with the twin-turbo V12 in the S600.
Production run
2005–2013
Engines covered
6
Avg. part price
—
19902026
Interactive systems map
Inspect the W221
Tap a hotspot to inspect that system
Systems map
Where it goes wrong
Each numbered hotspot counts the documented failure points in that area. Select one to see the specifics for this chassis and engine.
Failure points by system
Engine4
Cooling1
Intake3
Documented issues per engine
4M272
4M273
0M275
4M156
4M157
5OM642
Known weak points
What breaks on the W221
Balance shaft gear wear (2004–2008)Diagnose →Intake manifold swirl flap failureDiagnose →Timing chain / idler gear wearDiagnose →Camshaft adjuster magnetsDiagnose →Head bolt corrosion/stretchDiagnose →Camshaft and lifter wearDiagnose →Turbo oil linesDiagnose →Camshaft adjustersDiagnose →Oil cooler seal leak (classic)Diagnose →Swirl flap / intake runner failureDiagnose →
Guides & playbooks
W221 playbooks
Maintenance scheduleGive me a mileage-based maintenance schedule for a Mercedes-Benz S-Class W221, including the items the factory schedule skips.Buyer's inspectionI'm inspecting a used Mercedes-Benz S-Class W221. What exactly should I check, test drive and look for underneath?Build planPlan a staged performance build for a Mercedes-Benz S-Class W221 that stays reliable as a daily driver.Fault code lookupI have a fault code on my Mercedes-Benz S-Class W221. Walk me through what it means and how to confirm the cause.
Fits your W221
Parts & tools
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